Receptor regulation of osmolyte homeostasis in neural cells.

@article{Fisher2010ReceptorRO,
  title={Receptor regulation of osmolyte homeostasis in neural cells.},
  author={Stephen K. Fisher and Anne M. Heacock and Richard F. Keep and Daniel J Foster},
  journal={The Journal of physiology},
  year={2010},
  volume={588 Pt 18},
  pages={3355-64}
}
The capacity of cells to correct their volume in response to hyposmotic stress via the efflux of inorganic and organic osmolytes is well documented. However, the ability of cell-surface receptors, in particular G-protein-coupled receptors (GPCRs), to regulate this homeostatic mechanism has received much less attention. Mechanisms that underlie the regulation of cell volume are of particular importance to cells in the central nervous system because of the physical restrictions of the skull and… CONTINUE READING

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