Receptor mediated subversion of macrophage cytokine production by intracellular pathogens.

@article{Mosser1999ReceptorMS,
  title={Receptor mediated subversion of macrophage cytokine production by intracellular pathogens.},
  author={David M Mosser and Christopher L. Karp},
  journal={Current opinion in immunology},
  year={1999},
  volume={11 4},
  pages={406-11}
}
Appropriately regulated immune responses depend on the controlled production of cytokines from antigen presenting cells. IL-12 synthesis is tightly regulated by several redundant mechanisms. One mechanism of IL-12 regulation involves the cross-linking of surface receptors on macrophages. This pathway may be exploited by intracellular pathogens of… CONTINUE READING