Receptor-mediated endocytosis of iron-oxide particles provides efficient labeling of dendritic cells for in vivo MR imaging.

@article{Ahrens2003ReceptormediatedEO,
  title={Receptor-mediated endocytosis of iron-oxide particles provides efficient labeling of dendritic cells for in vivo MR imaging.},
  author={Eric T. Ahrens and Maryam Feili-Hariri and Haiyan Xu and Guillem Genov{\'e} and Penelope A. Morel},
  journal={Magnetic resonance in medicine},
  year={2003},
  volume={49 6},
  pages={1006-13}
}
Dendritic cells (DCs) function as antigen presenting cells in vivo and play a fundamental role in numerous diseases. New methods are described for high-efficiency intracellular labeling of DCs with superparamagnetic iron-oxide (SPIO) utilizing a receptor-mediated endocytosis (RME) mechanism. Bone marrow-derived DCs or a fetal skin-derived DC line were… CONTINUE READING