Receptor interactions, tropism, and mechanisms involved in morbillivirus-induced immunomodulation.

  title={Receptor interactions, tropism, and mechanisms involved in morbillivirus-induced immunomodulation.},
  author={J{\"u}rgen Schneider-Schaulies and Sibylle Schneider-Schaulies},
  journal={Advances in virus research},
Induction of immunomodulation and -suppression is a common feature of morbilliviruses such as measles virus (MV), rinderpest virus (RPV), and canine distemper virus (CDV) in their respective hosts. As major uptake receptor, signaling lymphocytic activation molecule (SLAM, CD150) essentially determines their tropism for immune cells, which is of considerable importance with regard to immunosuppression and the systemic spread to organs including secondary lymphoid organs, the skin, the… CONTINUE READING


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