Receptor interaction profiles of novel psychoactive tryptamines compared with classic hallucinogens
@article{Rickli2016ReceptorIP, title={Receptor interaction profiles of novel psychoactive tryptamines compared with classic hallucinogens}, author={A. Rickli and Olivier D. Moning and M. Hoener and M. Liechti}, journal={European Neuropsychopharmacology}, year={2016}, volume={26}, pages={1327-1337} }
The present study investigated interactions between the novel psychoactive tryptamines DiPT, 4-OH-DiPT, 4-OH-MET, 5-MeO-AMT, and 5-MeO-MiPT at monoamine receptors and transporters compared with the classic hallucinogens lysergic acid diethylamide (LSD), psilocin, N,N-dimethyltryptamine (DMT), and mescaline. We investigated binding affinities at human monoamine receptors and determined functional serotonin (5-hydroxytryptamine [5-HT]) 5-HT2A and 5-HT2B receptor activation. Binding at and the… CONTINUE READING
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