Receptor-interacting Protein 140 Overexpression Promotes Neuro-2a Neuronal Differentiation by ERK1/2 Signaling

@inproceedings{Feng2015ReceptorinteractingP1,
  title={Receptor-interacting Protein 140 Overexpression Promotes Neuro-2a Neuronal Differentiation by ERK1/2 Signaling},
  author={Xiao Feng and Weidong Yu and Rong Wei Liang and Cheng -Xian Shi and Zhuran Zhao and Jingzhu Guo},
  booktitle={Chinese medical journal},
  year={2015}
}
BACKGROUND Abnormal neuronal differentiation plays an important role in central nervous system (CNS) development abnormalities such as Down syndrome (DS), a disorder that results directly from overexpression of genes in trisomic cells. Receptor-interacting protein 140 (RIP140) is significantly upregulated in DS brains, suggesting its involvement in DS CNS… CONTINUE READING