Receptor imaging technique with 11C-labeled receptor ligands in living brain slices: its application to time-resolved imaging and saturation analysis of benzodiazepine receptor using [11C]Ro15-1788.

@article{Murata1996ReceptorIT,
  title={Receptor imaging technique with 11C-labeled receptor ligands in living brain slices: its application to time-resolved imaging and saturation analysis of benzodiazepine receptor using [11C]Ro15-1788.},
  author={Takahiko Murata and Kiyoshi Matsumura and Hirotaka Onoe and Mats Bergstr{\"o}m and Haruko Takechi and Sven Sihver and Wiebke Sihver and Henrik Neu and Yvonne Andersson and Mattias Ogren and Karl Johan Fasth and Bengt L{\aa}ngstr{\"o}m and Yasuyoshi Watanabe},
  journal={Neuroscience research},
  year={1996},
  volume={25 2},
  pages={145-54}
}
Recently we developed a novel imaging technique using positron emitter-labeled compounds as probes and a storage phosphor screen as a detector. This approach makes it possible to follow a variety of biochemical processes with spatial information in living brain slices. Further technical development is reported here in terms of time-resolved imaging and receptor characterization in a real equilibrium state. The method was validated by use of [11C]Ro15-1788, a benzodiazepine receptor antagonist… CONTINUE READING