Receptor-cyclase coupling protein in erythrocytes of patients with essential hypertension.

@article{Farfel1984ReceptorcyclaseCP,
  title={Receptor-cyclase coupling protein in erythrocytes of patients with essential hypertension.},
  author={Zvi Farfel and Adrian Iaina and Haskel E Eliahou and Z. Cohen},
  journal={Clinical science},
  year={1984},
  volume={67 1},
  pages={111-5}
}
In order to define the alteration of the function of the adrenergic system in hypertension, we studied directly the receptor-cyclase coupling protein (N protein), which is one of the components of the enzyme adenylate cyclase. N protein was determined in erythrocyte membranes of patients with essential hypertension and normal subjects, with a complementation assay in vitro. Fifteen normal subjects and 18 patients with essential hypertension (eight untreated and ten treated with beta… CONTINUE READING