Receptor binding specificity of recent human H3N2 influenza viruses

@article{Kumari2007ReceptorBS,
  title={Receptor binding specificity of recent human H3N2 influenza viruses},
  author={DR. P. V. Kamala Kumari and Shelly Gulati and David F. Smith and Upma Gulati and Richard D. Cummings and Gillian M. Air},
  journal={Virology Journal},
  year={2007},
  volume={4},
  pages={42 - 42}
}
Human influenza viruses are known to bind to sialic acid linked α2-6 to galactose, but the binding specificity beyond that linkage has not been systematically examined. H3N2 human influenza isolates lost binding to chicken red cells in the 1990s but viruses isolated since 2003 have re-acquired the ability to agglutinate chicken erythrocytes. We have investigated specificity of binding, changes in hemagglutinin sequence of the recent viruses and the role of sialic acid in productive infection… CONTINUE READING
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