Receptor binding properties of amperozide.

  title={Receptor binding properties of amperozide.},
  author={J O Svartengren and Per Simonsson},
  journal={Pharmacology & toxicology},
  volume={66 Suppl 1},
The receptor pharmacology of amperozide was investigated with in vitro radioligand binding technique. Amperozide possessed a high affinity to the 5-HT2 receptors (Ki = 16.5 +/- 2.1 nM) and a moderate affinity to alpha 1-adrenergic receptors of rat cerebral cortical membranes (Ki = 172 +/- 14 nM). The affinity of amperozide for striatal and limbic dopamine… CONTINUE READING