Receptor binding of norgestimate--a new orally active synthetic progestational compound.

Abstract

Binding of the new progestagen, norgestimate (D-(-)-13 beta-ethyl-17 beta-acetoxy-17-ethinyl-4-gonen-3-one-oxime), and its metabolites (levonorgestrel-3-oxime, levonorgestrel-17-acetate and levonorgestrel) to the progesterone receptor was investigated by competition experiments using cytosol from human myometrial tissue. Compared to R5020, a highly potent… (More)

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@article{Juchem1993ReceptorBO, title={Receptor binding of norgestimate--a new orally active synthetic progestational compound.}, author={Muriel Juchem and Kunhard Pollow and Walter Elger and Georg Hoffmann and Volker J Moebus}, journal={Contraception}, year={1993}, volume={47 3}, pages={283-94} }