Receptor-binding kinetics of A-14 and A-19 125I-labelled insulin.


Receptor-binding kinetics and degradation of tyrosine A-14 and A-19 125I-labelled insulin was studied using cultured human lymphocytes. Receptor-binding ability of A-14 insulin was 1.5-times as high as that of A-19 insulin. Dissociation from receptors on lymphocytes showed no difference between these two labelled insulins. In association studies percent… (More)


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@article{Watanabe1984ReceptorbindingKO, title={Receptor-binding kinetics of A-14 and A-19 125I-labelled insulin.}, author={N. Watanabe and M. Kobayashi and S Ohgaku and M. Iwasaki and Hitoshi Maegawa and Y. Shigeta}, journal={Biochimica et biophysica acta}, year={1984}, volume={798 3}, pages={313-6} }