Receptor-Mediated Choreography of Life and Death

@article{Bhardwaj2004ReceptorMediatedCO,
  title={Receptor-Mediated Choreography of Life and Death},
  author={A. Bhardwaj and B. Aggarwal},
  journal={Journal of Clinical Immunology},
  year={2004},
  volume={23},
  pages={317-332}
}
The cytokine tumor necrosis factor was originally identified as a protein that kills tumor cells. So far, 18 distinct members of this family have been identified. All of them regulate cell survival, proliferation, differentiation, and cell death, also called apoptosis. The apoptosis induced by TNF, and other members of the family, for example, FasL, VEGI, and TRAIL is mediated through death receptors. The apoptotic signals by these cytokines are transduced by eight different death domain- (DD… Expand
Death receptor signaling and its function in the immune system.
Death receptors: targets for cancer therapy.
Harnessing tumor necrosis factor receptors to enhance antitumor activities of drugs.
Redox regulation of apoptosis by members of the TNF superfamily.
TNF/TNF Receptors
Major apoptotic mechanisms and genes involved in apoptosis
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