Recent trends of HER-2 testing and trastuzumab therapy for breast cancer.

@article{Kurosumi2009RecentTO,
  title={Recent trends of HER-2 testing and trastuzumab therapy for breast cancer.},
  author={Masafumi Kurosumi},
  journal={Breast cancer},
  year={2009},
  volume={16 4},
  pages={284-7}
}
Molecular-targeted therapy using trastuzumab, a humanized monoclonal antibody against human epidermal growth factor receptor type-2 (HER-2), is considered to be effective for metastatic as well as primary breast cancer and has already become a worldwide standard therapy for patients with HER-2 protein over-expression and gene amplification. Pretreatment evaluation of HER-2 status is considered to be essential for selection of patients, and according to the generally used algorithm, cases with… CONTINUE READING
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