Recent progress in understanding Bartonella-induced vascular proliferation.

  title={Recent progress in understanding Bartonella-induced vascular proliferation.},
  author={Christoph Dehio},
  journal={Current opinion in microbiology},
  volume={6 1},
The ability to induce endothelial cell proliferation is a common feature of human pathogenic Bartonella species. Recent data have indicated that bartonellae can provoke angioproliferation by at least two independent mechanisms: directly, by triggering proliferation and inhibiting apoptosis of endothelial cells; and indirectly, by stimulating a paracrine angiogenic loop of vascular endothelial growth factor production by infected macrophages. A NF-kappaB-mediated acute inflammatory reaction of… CONTINUE READING

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