Recent progress in enzymatic resolution and desymmetrization of pharmaceuticals and their intermediates.

@article{Pesti2000RecentPI,
  title={Recent progress in enzymatic resolution and desymmetrization of pharmaceuticals and their intermediates.},
  author={Jaan A. Pesti and Robert Dicosimo},
  journal={Current opinion in drug discovery & development},
  year={2000},
  volume={6 6},
  pages={
          884-901
        }
}
The literature since August 2000 is surveyed for interesting and useful examples of the resolution or desymmetrization of pharmaceutical entities, their intermediates and potential drug precursors. Existing, putative and developmental drugs used in various therapeutic areas are discussed.