Recent progress in discovery and development of antimitotic agents.

@article{Kiselyov2007RecentPI,
  title={Recent progress in discovery and development of antimitotic agents.},
  author={Alexander Kiselyov and Konstantin V. Balakin and Sergey E. Tkachenko and Nikolay P. Savchuk and Alexandre V. Ivachtchenko},
  journal={Anti-cancer agents in medicinal chemistry},
  year={2007},
  volume={7 2},
  pages={189-208}
}
This review highlights structural diversity of antimitotic agents. In particular, we emphasized current antimitotic therapies based on modulation of microtubule dynamics. With several successful anticancer drugs on the market and numerous compounds in clinical developments, tubulin-binding agents remain among the most important categories of anticancer… CONTINUE READING