Recent perspectives in the diagnosis and evidence-based treatment of Mycoplasma genitalium

@article{Weinstein2012RecentPI,
  title={Recent perspectives in the diagnosis and evidence-based treatment of Mycoplasma genitalium},
  author={Scott A. Weinstein and Bradley G. Stiles},
  journal={Expert Review of Anti-infective Therapy},
  year={2012},
  volume={10},
  pages={487 - 499}
}
Mycoplasma genitalium is a globally important sexually transmitted pathogen. Men infected with M. genitalium frequently present with dysuria, while women may present with or without urogenital symptoms. In some populations, M. genitalium is significantly associated with HIV-1 infection, and is also an etiological agent in pelvic inflammatory disease. However, there is insufficient evidence to establish a causative role of the organism in obstetric complications, including tubal factor… Expand
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Mycoplasma genitalium: a review
TLDR
The association of M. genitalium with non-specific urethritis is now well established, but the evidence supporting its role in both male and female infertility remains inconclusive and the recommended treatment is azithromycin as a single 1 gm dose. Expand
Antimicrobial susceptibility of Mycoplasma genitalium isolates from Pretoria, South Africa in 2012 and 2016
TLDR
This study compared the genotypic macrolide and fluoroquinolone resistance of M. genitalium strains obtained from women attending a termination of pregnancy clinic five years apart to detect the presence of the pathogen by PCR in vaginal swab samples from two tertiary hospitals in Pretoria, South Africa. Expand
Mycoplasma genitalium Detection in Urogenital Specimens from Symptomatic and Asymptomatic Men and Women by Use of the cobas TV/MG Test
TLDR
The cobas assay was highly sensitive and specific in all relevant clinical samples for the detection of M. genitalium, and was compared to a reference standard of three laboratory-developed tests. Expand
Prevalence and correlates of Mycoplasma genitalium infection among prostatitis patients in Shanghai, China.
TLDR
M. genitalium was prevalent in the patients with prost atitis, particularly in those who received ineffective antibiotic treatment for the bacterium, and was identified as having a significant association of prostatitis. Expand
Urogenital mycoplasmosis and pregnancy
TLDR
Screening of asymptomatic patients for M. hominis, U. urealyticum and U. parvum is currently still not indicated, as no convincing causal relationship has been shown. Expand
Screening for Chlamydia trachomatis, Neisseria gonorrhoeae, and Mycoplasma genitalium should it be integrated into routine pregnancy care in French young pregnant women?
TLDR
The high prevalence of C. trachomatis in pregnant women aged ≤24 years, mostly asymptomatic, suggests that systematic screening could be beneficial, and the prevalence and risk factors for these bacterial infections are determined. Expand
Patients with cervical Ureaplasma Urealyticum and Chlamydia Trachomatis infection undergoing IVF/ICSI-ET: The need for new paradigm
Genital tract infections with ureaplasma urealyticum (UU) and chlamydia trachomatis (CT) are the most frequent sexually-transmitted disease worldwide. UU and CT infections are considered to be the… Expand
Patients with cervical Ureaplasma Urealyticum and Chlamydia Trachomatis infection undergoing IVF/ICSI-ET: The need for new paradigm
TLDR
Cervical UU and CT infections were the risk factors for ectopic pregnancy and tubal factor-induced infertility and the pregnancy rate, abortion rate, ectopicregnancy rate and premature birth rate in patients with UU/or CT infections showed no significant difference when compared with the control group. Expand
Epidemiology of Mycoplasma genitalium in British men and women aged 16–44 years: evidence from the third National Survey of Sexual Attitudes and Lifestyles (Natsal-3)
TLDR
This study strengthens evidence that MG is an STI, identified in over 1% of the population, including in men with high-risk behaviours in older age groups that are often not included in STI prevention measures. Expand
Study of the prevalence and association of ocular chlamydial conjunctivitis in women with genital infection by and attending outpatient clinic
  • 2016
AIM: To determine the association between chlamydial conjunctivitis and genital infection by and , in addition to the possible relationship between cultured bacterial pathogens and oculogenital… Expand
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