Recent mass spectrometry-based proteomics for biomarker discovery in lung cancer, COPD, and asthma

  title={Recent mass spectrometry-based proteomics for biomarker discovery in lung cancer, COPD, and asthma},
  author={Kiyonaga Fujii and H. Nakamura and T. Nishimura},
  journal={Expert Review of Proteomics},
  pages={373 - 386}
  • Kiyonaga Fujii, H. Nakamura, T. Nishimura
  • Published 2017
  • Medicine
  • Expert Review of Proteomics
  • ABSTRACT Introduction: Lung cancer and related diseases have been one of the most common causes of deaths worldwide. Genomic-based biomarkers may hardly reflect the underlying dynamic molecular mechanism of functional protein interactions, which is the center of a disease. Recent developments in mass spectrometry (MS) have made it possible to analyze disease-relevant proteins expressed in clinical specimens by proteomic challenges. Areas covered: To understand the molecular mechanisms of lung… CONTINUE READING
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