Recent investigations into pig antigen and anti-pig antibody expression.

Abstract

Genetic engineering of donor pigs to eliminate expression of the dominant xenogeneic antigen galactose α1,3 galactose (Gal) has created a sea change in the immunobiology of xenograft rejection. Antibody mediated xenograft rejection of GGTA-1 α-galactosyltransferase (GTKO) deficient organs is now directed to a combination of non-Gal pig protein and… (More)
DOI: 10.1016/j.ijsu.2015.07.724

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