Recent discoveries and developments of androgen receptor based therapy for prostate cancer

@article{Ramakrishnan2015RecentDA,
  title={Recent discoveries and developments of androgen receptor based therapy for prostate cancer},
  author={Elancheran Ramakrishnan and V Lenin Maruthanila and M. Ramanathan and Senthamaraikannan Kabilan and Rajlakshmi Devi and Ajaikumar B. Kunnumakara and Jibon Kotoky},
  journal={MedChemComm},
  year={2015},
  volume={6},
  pages={746-768}
}
The main focus of this review is to discuss the discoveries and developments of various therapies for prostate cancer. The AR has played an important role in prostate cancer growth and functions. This review discusses several groups of drugs that have sparingly good anti-cancer activities, as well as a similar structure and behaviour. A recent new-generation AR antagonist, Enzalutamide (MDV3100), has been approved for the treatment of advanced/metastatic prostate cancer. Nonsteroidal… 

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