Recent developments in the molecular genetics of malignant hyperthermia: implications for future diagnosis at the DNA level.

@article{Mccarthy1990RecentDI,
  title={Recent developments in the molecular genetics of malignant hyperthermia: implications for future diagnosis at the DNA level.},
  author={T. V. Mccarthy and J. M. Sandra Healy and Mary Lehane and James J. A. Heffron},
  journal={Acta anaesthesiologica Belgica},
  year={1990},
  volume={41 2},
  pages={107-12}
}
Molecular genetic linkage studies on the inherited human disorder malignant hyperthermia have resulted in the mapping of the locus for malignant hyperthermia susceptibility (MHS) to the twenty centimorgan genetic interval in the q12-13.2 region of chromosome 19 defined by the anonymous polymorphic DNA markers D19S9 and BCL3. The mapping of the MHS locus to… CONTINUE READING