Recent developments in streptogramin research.

  title={Recent developments in streptogramin research.},
  author={J. C. Barri{\`e}re and Nadine Berthaud and Diana Beyer and Sylvie Dutka-Malen and J. Molina Par{\'i}s and J F Desnottes},
  journal={Current pharmaceutical design},
  volume={4 2},
The streptogramins are a class of antibiotics remarkable for their antibacterial activity and their unique mechanism of action. These antibiotics are produced naturally, but the therapeutic use of the natural compounds is limited because they do not dissolve in water. New semisynthetic derivatives, in particular the injectable streptogramin quinupristin/dalfopristin, offer promise for treating the rising number of infections that are caused by multiply resistant bacteria. The streptogramins… CONTINUE READING
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