Recent developments in oncolytic adenovirus-based immunotherapeutic agents for use against metastatic cancers

Abstract

Recurrent or metastatic cancer in most cases remains an incurable disease, and thus alternative treatment strategies, such as oncolytic virotherapy, are of great interest for clinical application. Oncolytic adenoviruses (Ads) have many advantages as virotherapeutic agents and have been safely employed in the clinics. However, the efficacy of oncolytic Ads… (More)
DOI: 10.1038/cgt.2012.95

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