Recent development of Ori-Finder system and DoriC database for microbial replication origins.

@article{Luo2018RecentDO,
  title={Recent development of Ori-Finder system and DoriC database for microbial replication origins.},
  author={Hao Luo and Chun-Lan Quan and Chong Peng and Feng Gao},
  journal={Briefings in bioinformatics},
  year={2018}
}
DNA replication begins at replication origins in all three domains of life. Identification and characterization of replication origins are important not only in providing insights into the structure and function of the replication origins but also in understanding the regulatory mechanisms of the initiation step in DNA replication. The Z-curve method has been used in the identification of replication origins in archaeal genomes successfully since 2002. Furthermore, the Web servers of Ori-Finder… CONTINUE READING