Recent clinical experience with etodolac in the treatment of osteoarthritis of the knee

@article{Platt2005RecentCE,
  title={Recent clinical experience with etodolac in the treatment of osteoarthritis of the knee},
  author={P. N. Platt},
  journal={Clinical Rheumatology},
  year={2005},
  volume={8},
  pages={54-62}
}
  • P. Platt
  • Published 1 March 1989
  • Medicine
  • Clinical Rheumatology
SummaryInterim results are reported for three double-blind clinical trials comparing etodolac, a new nonsteroidal anti-inflammatory drug (NSAID), with piroxicam, diclofenac, or naproxen in patients with osteoarthritis (OA) of the knee. Patients assigned to receive etodolac were given 200 mg three times a day in the diclofenac comparison and 300 mg twice a day in the other two studies. The comparator groups in the three studies received piroxicam 20 mg once a day, diclofenac 50 mg three times a… 
Worldwide experience with etodolac (Lodine®) 300 mg b.i.d. in the treatment of osteoarthritis
  • P. Bacon
  • Medicine
    Rheumatology International
  • 2004
TLDR
The results reported in this review indicate that etodolac (300 mg b.i.d.) is effective and safe in the treatment of the signs and symptoms of OA and that it compares favorably with piroxicam, naproxen, indometrichacin, indomethacins sustained-release, and diclofenac SR.
Comparison of Clinical Effectiveness and Safety of Newer Nonsteroidal Anti-inflammatory Drugs in Patients of Osteoarthritis of Knee Joint: A Randomized, Prospective, Open-label Parallel-group Study
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The relative effectiveness, patient acceptability, costs and cost-effectiveness of four strategies for the prevention of non-steroidal anti-inflammatory drugs (NSAIDs)-induced gastrointestinal (GI) toxicity are assessed and Cox-1 NSAID plus H2RA is a dominant option.
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