Recent approaches in acute lymphoblastic leukemia in adults.

  title={Recent approaches in acute lymphoblastic leukemia in adults.},
  author={Nicola Goekbuget and Dieter Hoelzer},
  journal={Critical reviews in oncology/hematology},
  volume={36 1},
In the last decades outcome of adult acute lymphoblastic leukemia (ALL) has improved considerably. In large multicenter studies remission rates range from 75% to 89%, and long-term leukemia-free survival (LFS) from 28% to 39%. Major progress has also been made regarding better characterization of subtypes of ALL. Complete diagnostic procedures are essential to identify these subtypes which have significant differences in clinical and laboratory features and prognosis. LFS of > 50% can be… CONTINUE READING