Recent aging research in Caenorhabditis elegans.

  title={Recent aging research in Caenorhabditis elegans.},
  author={Elke Schaffitzel and Maren Hertweck},
  journal={Experimental gerontology},
  volume={41 6},
Evidence gathered over the past 15 years shows that the nematode Caenorhabditis elegans is excellently suited as a model to study aging processes in the entire organism. Genetic approaches have been used to identify and elucidate multiple mechanisms and their corresponding genes that limit the life span of C. elegans. These highly conserved pathways include the well-studied insulin/IGF-1 receptor-like signaling pathway, which is thought to be a central determinant of life span, since several… CONTINUE READING

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