Recent advances in topical ophthalmic drug delivery with lipid-based nanocarriers.

@article{Gan2013RecentAI,
  title={Recent advances in topical ophthalmic drug delivery with lipid-based nanocarriers.},
  author={Li Gan and Jing Wang and Min Jiang and Hanah Bartlett and Defang Ouyang and Frank Eperjesi and Jianping Liu and Yong Gan},
  journal={Drug discovery today},
  year={2013},
  volume={18 5-6},
  pages={
          290-7
        }
}
Ocular barriers and the poor water solubility of drug candidates present a number of problems for the development of ocular drug delivery systems. Recently, the emergence of lipid-based nanocarriers has provided a viable means of enhancing the bioavailability of ophthalmic formulations. A number of these formulations have been found to be clinically active and several others are currently undergoing clinical trials. In this review, the advantages of lipid-based nanocarriers as non-invasive… CONTINUE READING
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References

Publications referenced by this paper.
SHOWING 1-10 OF 64 REFERENCES

Edaravone-loaded liposomes for retinal protection against oxidative stress-induced retinal damage.

  • European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V
  • 2011

Preparation and evaluation of solid lipid nanoparticles of baicalin for ocular drug delivery system in vitro and in vivo

Z Liu
  • Drug Dev. Ind. Pharm
  • 2011