Recent advances in the understanding and management of diffuse large B-cell lymphoma in children.

@article{Reiter2008RecentAI,
  title={Recent advances in the understanding and management of diffuse large B-cell lymphoma in children.},
  author={A. Reiter and Wolfram Klapper},
  journal={British journal of haematology},
  year={2008},
  volume={142 3},
  pages={329-47}
}
Diffuse large B-cell lymphomas (DLBCL) are neoplasms of transformed mature B cells, accounting for approximately 10% of non-Hodgkin lymphomas (NHL) of childhood. Increasing evidence indicates that DLBCL are composed of biologically distinct subsets. Clinical features of children with DLBCL differ from those with other NHL entities, e.g. by a lower frequency of bone-marrow and central nervous system involvement. Treatment strategies originally designed for Burkitt lymphoma appear to be… CONTINUE READING

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Pathology and Genetics of Tumours of Haematopoetic and Lymphoid Tissues

  • E. Jaffe, N. Harris, H. Stein, J. W. Vardiman
  • 2001
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