Recent advances in the pathophysiology of acute pain.

@article{Woolf1989RecentAI,
  title={Recent advances in the pathophysiology of acute pain.},
  author={C. Woolf},
  journal={British journal of anaesthesia},
  year={1989},
  volume={63 2},
  pages={
          139-46
        }
}
  • C. Woolf
  • Published 1989
  • Medicine
  • British journal of anaesthesia
The peripheral receptors of the sensory systems have transduction mechanisms that ensure maximal sensitivity to only a small spectrum of the wide range of stimuli that impinge upon them. Because there is a minimal overlap in sensitivity between the receptors of the different sensory systems, each is specialized and possesses its own "specific" or "adequate" stimulus. Maintaining this receptor-generated specificity, sensory pathways in the central nervous system are, to a considerable extent… Expand

Paper Mentions

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From acute to chronic pain: mechanisms and hypotheses.
Chapter 4 – Somatosensory System
Pain: current aspects on peripheral and central sensitization.
Somatic pain--pathogenesis and prevention.
  • C. Woolf
  • Medicine
  • British journal of anaesthesia
  • 1995
Pain Relief Before Pain Starts
Dynamic alterations in the cutaneous mechanoreceptive fields of dorsal horn neurons in the rat spinal cord
  • C. Woolf, A. King
  • Chemistry, Medicine
  • The Journal of neuroscience : the official journal of the Society for Neuroscience
  • 1990
Spinal Pain Mechanisms
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Physiological, inflammatory and neuropathic pain.
  • C. Woolf
  • Medicine
  • Advances and technical standards in neurosurgery
  • 1987
Cutaneous Mechanoreceptors and Nociceptors
Relative effectiveness of C primary afferent fibers of different origins in evoking a prolonged facilitation of the flexor reflex in the rat
  • C. Woolf, P. Wall
  • Medicine
  • The Journal of neuroscience : the official journal of the Society for Neuroscience
  • 1986
Central projections of identified, unmyelinated (C) afferent fibers innervating mammalian skin.
Central terminations of cutaneous mechanoreceptive afferents in the rat lumbar spinal cord
  • C. Woolf
  • Biology, Medicine
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  • 1987
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