Recent advances in the neurobiology of depression.

  title={Recent advances in the neurobiology of depression.},
  author={Charles B. Nemeroff},
  journal={Psychopharmacology bulletin},
  volume={36 Suppl 2},
Elucidation of the neurobiological basis of depression and other mood disorders is rapidly increasing. Considerable experimental and clinical evidence supports the fundamental roles of serotonin and norepinephrine, as well as the interactions between these systems in the etiology of depression. Substantial evidence has accrued, including changes in neurotransmitter and neurotransmitter metabolite concentrations, reuptake sites, and receptors, to support the hypothesis that alteration in… CONTINUE READING
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