Recent advances in the immunology of xenotransplantation

@article{Takahashi1997RecentAI,
  title={Recent advances in the immunology of xenotransplantation},
  author={Tohru Takahashi and Soheyla Saadi and Jeffrey L Platt},
  journal={Immunologic Research},
  year={1997},
  volume={16},
  pages={273-297}
}
The transplantation of tissue and organs between individuals of different species, that is xenotransplantation, engenders a variety of severe immune responses. Xenogeneic immune responses mediated by naturally occurring antibodies and complement lead to hyperacute and acute vascular rejection of vascularized organ grafts and may also cause vascular rejection of cell and tissue grafts. Under some circumstances, however, a vascularized organ graft may evade humoral rejection despite the presence… Expand
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