Recent advances in the biosynthesis of penicillins, cephalosporins and clavams and its regulation.

@article{Ozcengiz2013RecentAI,
  title={Recent advances in the biosynthesis of penicillins, cephalosporins and clavams and its regulation.},
  author={Gulay Ozcengiz and Arnold L. Demain},
  journal={Biotechnology advances},
  year={2013},
  volume={31 2},
  pages={287-311}
}
The beta-lactam antibiotics have been serving mankind for over 70 years. Despite this old age, they continue to provide health to the world population by virtue of industrial production and discoveries of new secondary metabolite molecules with useful activities. Sales of these remarkable compounds have reached over $20 billion dollars per year. They include penicillins, cephalosporins, cefoxitin, monobactams, clavulanic acid and carbapenems. Strain improvement of the penicillin-producing… CONTINUE READING
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