Recent advances in the biology and drug targeting of malaria parasite aminoacyl-tRNA synthetases

@article{Khan2016RecentAI,
  title={Recent advances in the biology and drug targeting of malaria parasite aminoacyl-tRNA synthetases},
  author={Sameena M Khan},
  journal={Malaria Journal},
  year={2016},
  volume={15},
  pages={1-10}
}
Escalating drug resistance in malaria parasites and lack of vaccine entails the discovery of novel drug targets and inhibitor molecules. The multi-component protein translation machinery is a rich source of such drug targets. Malaria parasites contain three translational compartments: the cytoplasm, apicoplast and mitochondrion, of which the latter two are of the prokaryotic type. Recent explorations by many groups into the malaria parasite protein translation enzymes, aminoacyl-tRNA… CONTINUE READING
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