Recent advances in synthetic biology for engineering isoprenoid production in yeast.

@article{Vickers2017RecentAI,
  title={Recent advances in synthetic biology for engineering isoprenoid production in yeast.},
  author={Claudia E Vickers and Thomas C Williams and Bingyin Peng and Joel Cherry},
  journal={Current opinion in chemical biology},
  year={2017},
  volume={40},
  pages={47-56}
}
Isoprenoids (terpenes/terpenoids) have many useful industrial applications, but are often not produced at industrially viable level in their natural sources. Synthetic biology approaches have been used extensively to reconstruct metabolic pathways in tractable microbial hosts such as yeast and re-engineer pathways and networks to increase yields. Here we review recent advances in this field, focusing on central carbon metabolism engineering to increase precursor supply, re-directing carbon flux… CONTINUE READING