Recent advances in studies of spontaneous activity in smooth muscle: ubiquitous pacemaker cells.

@article{Takaki2010RecentAI,
  title={Recent advances in studies of spontaneous activity in smooth muscle: ubiquitous pacemaker cells.},
  author={Miyako Takaki and Hikaru Suzuki and Shinsuke Nakayama},
  journal={Progress in biophysics and molecular biology},
  year={2010},
  volume={102 2-3},
  pages={
          129-35
        }
}
The general and specific properties of pacemaker cells, including Kit-negative cells, that are distributed in gastrointestinal, urethral and uterine smooth muscle tissues, are discussed herein. In intestinal tissues, interstitial cells of Cajal (ICC) are heterogeneous in both their forms and roles. ICC distributed in the myenteric layer (ICC-MY) act as primary pacemaker cells for intestinal mechanical and electrical activity. ICC distributed in muscle bundles play a role as mediators of signals… CONTINUE READING
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