Recent advances in single-cell studies of gene regulation.

Abstract

A mechanistic understanding of gene regulatory network dynamics requires quantitative single-cell data of multiple network components in response to well-defined perturbations. Recent advances in the development of fluorescent biomarkers for proteins, detection of RNA and interactions, microfluidic technology, and high-resolution imaging have set the stage… (More)
DOI: 10.1016/j.copbio.2011.11.006

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