Recent advances in retromer biology.

@article{McGough2011RecentAI,
  title={Recent advances in retromer biology.},
  author={Ian J McGough and Peter J. Cullen},
  journal={Traffic},
  year={2011},
  volume={12 8},
  pages={963-71}
}
The endosomal network is an organized array of intracellular, membranous compartments that function as sorting sites for endosomal and biosynthetic cargo. The fate of endocytic cargo is reliant upon interactions with a number of molecularly distinct sorting complexes, which tightly control the relationship between sorting of their respective cargo and the physical process of membrane re-scuplturing required for the formation of transport carries. One such complex, retromer, mediates retrograde… CONTINUE READING

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