Recent advances in paediatric neuro-oncology.

  title={Recent advances in paediatric neuro-oncology.},
  author={Frank H. Saran},
  journal={Current opinion in neurology},
  volume={15 6},
PURPOSE OF REVIEW Primary central nervous system malignancies incorporate a variety of tumours with diverse biology and clinical behaviour and represent the most common solid tumour entity of childhood, accounting for approximate 20-25% of all primary paediatric malignancies. Recent findings regarding the underlying tumour biology may open up new avenues of clinical trial design, particularly identifying possible targets for biological modifiers. Over the last 12-18 months a significant number… CONTINUE READING


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