Recent advances in hematopoietic stem cell biology.

  title={Recent advances in hematopoietic stem cell biology.},
  author={Jesper Bonde and David A Hess and Jan A Nolta},
  journal={Current opinion in hematology},
  volume={11 6},
PURPOSE OF REVIEW Exciting advances have been made in the field of hematopoietic stem cell biology during the past year. This review summarizes recent progress in the identification, culture, and in vivo tracking of hematopoietic stem cells. RECENT FINDINGS The roles of Wnt and Notch proteins in regulating stem cell renewal in the microenvironment, and how these molecules can be exploited in ex vivo stem cell culture, are reviewed. The importance of identification of stem cells using… CONTINUE READING