Recent advances in genetic code engineering in Escherichia coli.

  title={Recent advances in genetic code engineering in Escherichia coli.},
  author={Michael Georg Hoesl and Nediljko Budisa},
  journal={Current opinion in biotechnology},
  volume={23 5},
The expansion of the genetic code is gradually becoming a core discipline in Synthetic Biology. It offers the best possible platform for the transfer of numerous chemical reactions and processes from the chemical synthetic laboratory into the biochemistry of living cells. The incorporation of biologically occurring or chemically synthesized non-canonical amino acids into recombinant proteins and even proteomes via reprogrammed protein translation is in the heart of these efforts. Orthogonal… CONTINUE READING
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