Recent advances in elucidating pain mechanisms

@article{Vadivelu2005RecentAI,
  title={Recent advances in elucidating pain mechanisms},
  author={Nalini Vadivelu and Raymond S. Sinatra},
  journal={Current Opinion in Anaesthesiology},
  year={2005},
  volume={18},
  pages={540–547}
}
Purpose of review The purpose of this review is to highlight the important recent advances in this fast developing field of pain mechanisms. It is now recognized that acute tissue and neural injuries can result in nociceptor sensitization (primary hyperalgesia) and spinal cord hyperexcitability or central sensitization that results in secondary hyperalgesia and allodynia. Recent findings New findings regarding peripheral and central sensitization are presented in this review. Newer ideas on… 

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