Recent advances in dynamic m6A RNA modification

@inproceedings{Cao2016RecentAI,
  title={Recent advances in dynamic m6A RNA modification},
  author={Guangchao Cao and Hua-Bing Li and Zhinan Yin and Richard A Flavell},
  booktitle={Open biology},
  year={2016}
}
The identification of m(6)A demethylases and high-throughput sequencing analysis of methylated transcriptome corroborated m(6)A RNA epigenetic modification as a dynamic regulation process, and reignited its investigation in the past few years. Many basic concepts of cytogenetics have been revolutionized by the growing understanding of the fundamental role of m(6)A in RNA splicing, degradation and translation. In this review, we summarize typical features of methylated transcriptome in mammals… CONTINUE READING

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References

Publications referenced by this paper.
SHOWING 1-10 OF 74 REFERENCES

RNA epigenetics

A Klungland, JA Dahl
  • Transl . Res .
  • 2015

Stem cells . m 6 A mRNA methylation facilitates resolution of naive pluripotency toward differentiation

N Liu, T Pan
  • Science
  • 2015

The biology of innate lymphoid cells

K Kariko, M Buckstein, H Ni, D Weissman
  • Nature
  • 2015

Dynamic RNA modifications in disease

S Blanco, M Frye
  • Curr . Opin . Genet . Dev .
  • 2014