Recent advances in chemical proteomics: exploring the post-translational proteome.

@article{Tate2008RecentAI,
  title={Recent advances in chemical proteomics: exploring the post-translational proteome.},
  author={Edward W Tate},
  journal={Journal of chemical biology},
  year={2008},
  volume={1 1-4},
  pages={17-26}
}
Identification and quantification of multiple proteins from complex mixtures is a central theme in post-genomic biology. Despite recent progress in high-throughput proteomics, proteomic analysis of post-translationally modified (PTM) proteins remains particularly challenging. This mini-review introduces the emerging field of chemical proteomics and reviews recent advances in chemical proteomic technology that are offering striking new insights into the functional biology of post-translational… CONTINUE READING