Recent advances in biological therapy for inflammatory bowel disease.

  title={Recent advances in biological therapy for inflammatory bowel disease.},
  author={Jelica Kurtovic and Isidor Segal},
  journal={Tropical gastroenterology : official journal of the Digestive Diseases Foundation},
  volume={25 1},
Immune system is a major determinant of pathophysiology of inflammatory bowel disease (IBD), and cytokines are well known mediators of immune system. Recently, informations on pro-inflammatory cytokines and their role in IBD have led to development of potential therapeutic approach to manipulate these cytokines and there by inhibiting inflammation in IBD. These therapeutic approaches include inhibitors of the tumour necrosis factor (TNF)-alpha lymphocyte trafficking, type 1 T helper (Th1) cell… CONTINUE READING


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