Recent advances in Ca(2+)-dependent Ras regulation and cell proliferation.

Abstract

Our understanding of the mechanisms whereby growth factors stimulate cell proliferation through the Ras pathway stems largely from studies of the canonical pathway involving recruitment of Ras activators and inhibitors to the vicinity of receptor tyrosine kinases via phosphotyrosine-binding adaptor proteins. Ca(2+) has seldom joined the party, despite the… (More)

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@article{Cook2006RecentAI, title={Recent advances in Ca(2+)-dependent Ras regulation and cell proliferation.}, author={Simon J Cook and Peter J. Lockyer}, journal={Cell calcium}, year={2006}, volume={39 2}, pages={101-12} }