Recent Advances in Tryptophan Research

  title={Recent Advances in Tryptophan Research},
  author={G. Filippini and C. Costa and A. Bertazzo},
  booktitle={Advances in Experimental Medicine and Biology},
  • G. Filippini, C. Costa, A. Bertazzo
  • Published in
    Advances in Experimental…
  • Chemistry
  • A high percentage of patients with human immunodeficiency virus infection presents with decreased tryptophan concentrations in serum and cerebrospinal fluid. In parallel degradation products of tryptophan like kynurenine and quinolinic acid are increased. We investigated the behavior of tryptophan concentrations in 14 patients with HIV infection before and during treatment with zidovudine, and we found a significant increase of tryptophan in serum and cerebrospional fluid after 4-14 months of… CONTINUE READING
    43 Citations

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