Recent Advances, Challenges, and Opportunities in Synthetic Genomes

  title={Recent Advances, Challenges, and Opportunities in Synthetic Genomes},
  author={V. Singh},
  • V. Singh
  • Published 2020
  • Biology
  • Synthetic genomics is a newly emerging area of synthetic biology that allows us to design, synthesize, and construct a desired genome to create new synthetic life forms. It has been possible because of recently developed advanced cloning and DNA synthesis technologies. Synthetic genomes of bacteria, viruses, and yeast have been chemically synthesized and characterized. Synthetic viruses have been designed and constructed in a way that alters the pathogenicity but maintains antigenicity for… CONTINUE READING


    Synthetic Genomics: From DNA Synthesis to Genome Design.
    • 19
    Engineering the ribosomal DNA in a megabase synthetic chromosome
    • 96
    • PDF
    Total Synthesis of a Functional Designer Eukaryotic Chromosome
    • 386
    • PDF
    Genome-wide engineering of an infectious clone of herpes simplex virus type 1 using synthetic genomics assembly methods
    • 25
    • PDF
    Design of a synthetic yeast genome
    • 264
    • PDF
    Design and synthesis of a minimal bacterial genome
    • 713
    • PDF
    Bug mapping and fitness testing of chemically synthesized chromosome X
    • 125
    • PDF
    Synthetic poliovirus and other designer viruses: what have we learned from them?
    • 29