Receiver-operating characteristic curve analysis in diagnostic, prognostic and predictive biomarker research

  title={Receiver-operating characteristic curve analysis in diagnostic, prognostic and predictive biomarker research},
  author={Kjetil S{\o}reide},
  journal={Journal of Clinical Pathology},
  pages={1 - 5}
  • K. Søreide
  • Published 22 September 2008
  • Medicine, Biology
  • Journal of Clinical Pathology
#### Take-home messages From a clinical perspective, biomarkers may have a variety of functions, which correspond to different stages (table 1) in disease development, such as in the progression in cancer or cardiovascular disease.1 2 Biomarkers can assist in the care of patients who are asymptomatic (screening biomarkers), those who are suspected to have the disease (diagnostic biomarkers) and those with overt disease (prognostic biomarkers) for whom therapy may or may not have been initiated… 

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